EpiCom¶
An implementation of chemical-based mechanism enrichment with NeuroMMSig described by [Hoyt2018].
This algorithm has multiple steps:
- Select NeuroMMSig networks for AD, PD, and epilepsy
- Select drugs from DrugBank, and their targets
- Run NeuroMMSig algorithm on target list for each network and each mechanism
- Store in database
[Hoyt2018] | Hoyt, C. T., et al. (2018) A systematic approach for identifying shared mechanisms in epilepsy and its comorbidities, Database, Volume 2018, 1 January 2018, bay050 |