EpiCom¶
An implementation of chemical-based mechanism enrichment with NeuroMMSig described by [Hoyt2018].
This algorithm has multiple steps:
Select NeuroMMSig networks for AD, PD, and epilepsy
Select drugs from DrugBank, and their targets
Run NeuroMMSig algorithm on target list for each network and each mechanism
Store in database
- Hoyt2018
Hoyt, C. T., et al. (2018) A systematic approach for identifying shared mechanisms in epilepsy and its comorbidities, Database, Volume 2018, 1 January 2018, bay050